Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786540 | 0.89 | KMT2A (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28484707 | 0.88 | PDE4B (0.48) | PDE4BTDP1POLBHTTKMT2A | |
| SCHEMBL17933774 | 0.88 | KMT2A (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28478128 | 0.87 | HIF1A (0.49) | PDE4BALDH1A1TDP1POLBKMT2A | |
| SCHEMBL28479954 | 0.87 | PDE4B (0.47) | PDE4BALDH1A1TDP1POLBHTT | |
| SCHEMBL28479695 | 0.86 | HIF1A (0.52) | PDE4BTDP1POLBHTTKMT2A | |
| SCHEMBL28481675 | 0.84 | PDE4B (0.55) | PDE4BALDH1A1POLBKMT2AHPGD | |
| SCHEMBL28901969 | 0.83 | PDE4B (0.51) | PDE4BALDH1A1TDP1POLBKMT2A | |
| SCHEMBL28487133 | 0.81 | PDE4B (0.60) | PDE4BPOLBHPGD | |
| SCHEMBL28484061 | 0.80 | ALDH1A1 (0.52) | PDE4BALDH1A1POLBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954664-A | Cystic fibrosis transmembrane conductance regulator and methods of use | 艾伯维海外有限公司 | 2020-11-17 | — | — | CN | disclosed |