Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28478306 | 0.88 | CA12 (0.53) | PDE4BHPGDPOLBHTTKMT2A | |
| SCHEMBL28479954 | 0.87 | PDE4B (0.47) | PDE4BHPGDPOLBHTTKMT2A | |
| SCHEMBL3786540 | 0.86 | KMT2A (0.53) | PDE4BHPGDPOLBHTTKMT2A | |
| SCHEMBL17933774 | 0.82 | KMT2A (0.53) | HPGDHTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL28478128 | 0.82 | HIF1A (0.49) | PDE4BHPGDPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL28478130 | 0.81 | PDE4B (0.49) | PDE4BHPGDPOLBKMT2AL3MBTL1 | |
| SCHEMBL28479695 | 0.81 | HIF1A (0.52) | PDE4BHPGDPOLBHTTKMT2A | |
| SCHEMBL28481675 | 0.79 | PDE4B (0.55) | PDE4BHPGDPOLBKMT2AL3MBTL1 | |
| SCHEMBL28487652 | 0.78 | ALDH1A1 (0.44) | PDE4BHPGDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL28901969 | 0.78 | PDE4B (0.51) | PDE4BHPGDPOLBKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954664-A | Cystic fibrosis transmembrane conductance regulator and methods of use | 艾伯维海外有限公司 | 2020-11-17 | — | — | CN | disclosed |