Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 10/20 | 0.60 |
| ▸ | PDE4A | P27815 | 7/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | QDPR | P09417 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479794 | 0.94 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL28486348 | 0.91 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL28491678 | 0.89 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL28481675 | 0.81 | PDE4B (0.55) | PDE4BHPGDPOLB | |
| SCHEMBL28478306 | 0.81 | CA12 (0.53) | PDE4BHPGDPOLB | |
| SCHEMBL28901969 | 0.80 | PDE4B (0.51) | PDE4BHPGDPOLB | |
| SCHEMBL1494013 | 0.80 | NR3C1 (0.64) | PDE4BPDE4APDE4CPDE4DQDPR | |
| Ammonia Solution, Strong SCHEMBL7288975 | 0.78 | NR3C1 (0.62) | PDE4BPDE4APDE4CPDE4DQDPR | |
| SCHEMBL28478130 | 0.78 | PDE4B (0.49) | PDE4BHPGDPOLBHIF1A | |
| SCHEMBL28489873 | 0.78 | ALDH1A1 (0.51) | PDE4BHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954664-A | Cystic fibrosis transmembrane conductance regulator and methods of use | 艾伯维海外有限公司 | 2020-11-17 | — | — | CN | disclosed |