Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 9/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13271229 | 0.80 | P4HB (0.46) | P4HBEGFRERN1TRPV1KDM4E | |
| SCHEMBL3239306 | 0.80 | P4HB (0.40) | P4HBEGFRKDM4E | |
| SCHEMBL25850566 | 0.79 | EGFR (0.48) | P4HBEGFRTRPV1KDM4E | |
| SCHEMBL13313256 | 0.76 | ALDH1A1 (0.58) | ERN1KDM4E | |
| SCHEMBL276426 | 0.75 | METAP2 (0.55) | EGFRTRPV1KDM4EMAPKAPK2 | |
| SCHEMBL3265420 | 0.74 | RPS6KB1 (0.43) | — | |
| SCHEMBL13406017 | 0.74 | P4HB (0.37) | P4HBEGFRTRPV1 | |
| SCHEMBL13313265 | 0.74 | EGLN1 (0.42) | P4HB | |
| Hydrochloric Acid SCHEMBL28754132 | 0.73 | METAP2 (0.53) | EGFRTRPV1KDM4EMAPKAPK2 | |
| SCHEMBL13406059 | 0.72 | P4HB (0.36) | P4HBEGFRERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108383849-B | Imidazoquinazoline derivative and application thereof in anti-tumor and anti-inflammation | 浙江大学 | 2020-11-06 | — | — | CN | disclosed |