Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600744 | 0.84 | GPR35 (0.47) | MEN1KMT2AGPR35TDP1RAB9A | |
| SCHEMBL27850556 | 0.82 | TDP1 (0.49) | MEN1KMT2AGPR35TDP1RAB9A | |
| SCHEMBL5690942 | 0.82 | KMT2A (0.41) | KMT2ARAB9AERN1NPSR1NPC1 | |
| SCHEMBL27479661 | 0.81 | HSPB1 (0.48) | HSPB1MEN1KMT2AGPR35TDP1 | |
| SCHEMBL4090307 | 0.80 | HSPB1 (0.47) | HSPB1MEN1KMT2AGPR35TDP1 | |
| SCHEMBL28920607 | 0.80 | HSPB1 (0.47) | HSPB1MEN1KMT2AGPR35TDP1 | |
| SCHEMBL4087050 | 0.79 | HSPB1 (0.46) | HSPB1MEN1KMT2AGPR35TDP1 | |
| SCHEMBL2012344 | 0.78 | HSPB1 (0.48) | HSPB1MEN1KMT2AGPR35TDP1 | |
| SCHEMBL27799012 | 0.76 | RAB9A (0.39) | MEN1KMT2AGPR35TDP1RAB9A | |
| SCHEMBL4087052 | 0.75 | HSPB1 (0.43) | HSPB1MEN1KMT2AGPR35TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886234-B | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-111886234-A | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2020-11-03 | — | — | CN | disclosed |