Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 10/20 | 0.70 |
| ▸ | NOS3 | P29474 | 8/20 | 0.70 |
| ▸ | NOS1 | P29475 | 8/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902465 | 1.00 | NOS2 (0.70) | NOS2NOS3NOS1MEN1KMT2A | |
| SCHEMBL28479289 | 0.87 | SMN1; SMN2 (0.59) | NOS2NOS3NOS1MEN1KMT2A | |
| SCHEMBL28479291 | 0.87 | SMN1; SMN2 (0.59) | NOS2NOS3NOS1MEN1KMT2A | |
| SCHEMBL25497554 | 0.85 | SMN1; SMN2 (0.79) | SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL28486682 | 0.85 | SMN1; SMN2 (0.79) | SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL28486683 | 0.85 | SMN1; SMN2 (0.79) | SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL28483947 | 0.85 | KMT2A (0.70) | NOS2NOS3NOS1MEN1KMT2A | |
| SCHEMBL28483945 | 0.85 | KMT2A (0.70) | NOS2NOS3NOS1MEN1KMT2A | |
| SCHEMBL28481411 | 0.85 | NOS3 (0.72) | NOS2NOS3NOS1SMN1; SMN2TAS1R3 | |
| SCHEMBL28481413 | 0.85 | NOS3 (0.72) | NOS2NOS3NOS1SMN1; SMN2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111807983-A | Cinnamic acid derivative and preparation method thereof | 五邑大学 | 2020-10-23 | — | — | CN | claimed |
| CN-111807983-B | Cinnamic acid derivative and preparation method thereof | 五邑大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-111807983-A | Cinnamic acid derivative and preparation method thereof | 五邑大学 | 2020-10-23 | — | — | CN | disclosed |