SCHEMBL28480307

SCHEMBL28480307

O=Cc1cccc(C2CCCCC2)c1C1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CEL P19835 2/20 0.38
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
THRB P10828 1/20 0.37
BLM P54132 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.36
ALDH1A1 P00352 1/20 0.36
PTGS2 P35354 1/20 0.36
ABCB1 P08183 2/20 0.35
SRC P12931 1/20 0.34
ERN1 O75460 3/20 0.33
KMO O15229 1/20 0.33
HTR1A P08908 1/20 0.33
HTR7 P34969 1/20 0.33
POLB P06746 1/20 0.32
CASP3 P42574 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29452927 0.85 PTGS2 (0.38) CELMEN1LMNATHRBBLM
SCHEMBL548377 0.85 CEL (0.37) CELMEN1LMNATHRBBLM
SCHEMBL14236917 0.83 MEN1 (0.46) CELMEN1LMNATHRBBLM
SCHEMBL22284134 0.83 MEN1 (0.46) CELMEN1LMNATHRBBLM
SCHEMBL21647623 0.83 MEN1 (0.46) CELMEN1LMNATHRBBLM
SCHEMBL11675315 0.83 MEN1 (0.46) CELMEN1LMNATHRBBLM
SCHEMBL197356 0.83 MEN1 (0.46) CELMEN1LMNATHRBBLM
SCHEMBL14237042 0.83 MEN1 (0.46) CELMEN1LMNATHRBBLM
SCHEMBL4070687 0.82 ABCB1 (0.35) CELPTGDR2ALDH1A1PTGS2ABCB1
SCHEMBL547607 0.81 LMNA (0.48) CELMEN1LMNATHRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111393832-A Macromolecular network topological heterogeneous system based on dynamic covalent bonds and application method thereof 浙江大学 2020-07-10 CN disclosed