Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569032 | 0.80 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1LMNAALOX15TSHR | |
| SCHEMBL18420016 | 0.80 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1LMNAALOX15TSHR | |
| SCHEMBL6319718 | 0.80 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1LMNAALOX15TSHR | |
| SCHEMBL14110422 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1L3MBTL1LMNAALOX15TSHR | |
| SCHEMBL2170056 | 0.78 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1LMNAALOX15TSHR | |
| SCHEMBL836745 | 0.78 | SMN1; SMN2 (0.65) | ALDH1A1L3MBTL1LMNAALOX15TSHR | |
| SCHEMBL28727291 | 0.78 | SMN1; SMN2 (0.65) | ALDH1A1L3MBTL1LMNAALOX15TSHR | |
| SCHEMBL20662517 | 0.78 | ALOX15 (0.63) | ALDH1A1L3MBTL1LMNAALOX15TSHR | |
| SCHEMBL19031391 | 0.77 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1LMNAALOX15TSHR | |
| Hydrochloric Acid SCHEMBL3610419 | 0.77 | SMN1; SMN2 (0.63) | ALDH1A1L3MBTL1LMNAALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902415-A | Pharmaceutical compounds | 大冢制药株式会社 | 2020-11-06 | — | — | CN | claimed |
| CN-111902415-A | Pharmaceutical compounds | 大冢制药株式会社 | 2020-11-06 | — | — | CN | disclosed |