SCHEMBL569032

SCHEMBL569032

CC(=O)c1nc2ccccc2s1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.67
RECQL P46063 2/20 0.65
THRB P10828 1/20 0.65
L3MBTL1 Q9Y468 3/20 0.61
TSHR P16473 2/20 0.61
ALOX15 P16050 1/20 0.61
CASP1 P29466 1/20 0.61
LMNA P02545 1/20 0.61
RAB9A P51151 6/20 0.58
NPC1 O15118 5/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
HPGD P15428 2/20 0.58
PKM P14618 2/20 0.58
NFKB1 P19838 2/20 0.58
NFKB2 Q00653 2/20 0.58
RELA Q04206 2/20 0.58
ADORA1 P30542 1/20 0.57
DYRK1A Q13627 1/20 0.57
MAPT P10636 5/20 0.57
CYP1A2 P05177 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19031391 0.85 ALDH1A1 (0.63) ALDH1A1RECQLTHRBL3MBTL1TSHR
SCHEMBL6319718 0.84 ALDH1A1 (0.66) ALDH1A1RECQLTHRBL3MBTL1TSHR
SCHEMBL28727291 0.82 SMN1; SMN2 (0.65) ALDH1A1RECQLTHRBL3MBTL1TSHR
SCHEMBL2170056 0.82 ALDH1A1 (0.64) ALDH1A1RECQLTHRBL3MBTL1TSHR
SCHEMBL836745 0.82 SMN1; SMN2 (0.65) ALDH1A1RECQLTHRBL3MBTL1TSHR
SCHEMBL23617613 0.81 NPC1 (0.63) ALDH1A1RECQLTHRBL3MBTL1TSHR
SCHEMBL21865146 0.81 THRB (0.65) ALDH1A1RECQLTHRBL3MBTL1TSHR
SCHEMBL12545749 0.81 RECQL (0.65) ALDH1A1RECQLTHRBL3MBTL1TSHR
SCHEMBL369480 0.81 ALDH1A1 (0.62) ALDH1A1RECQLTHRBL3MBTL1TSHR
Hydrochloric Acid SCHEMBL3610419 0.81 SMN1; SMN2 (0.63) ALDH1A1RECQLTHRBL3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118880329-A Acidic copper salt roughening solution for precisely regulating and controlling roughness of copper foil and roughening method 长江师范学院 2024-11-01 CN claimed
CN-108395428-B Benzothiazole-triazole-isatin type compound and synthesis and application thereof 贵州医科大学 2021-02-02 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
CN-102010427-A Method for preparing cefdinir CHINA UNION CHEMPHARMA SUZHOU CO LTD 2011-04-13 CN claimed
CN-101974020-A Method for synthesizing cefdinir CHINA UNION CHEMPHARMA SUZHOU CO LTD 2011-02-16 CN claimed
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US claimed
EP-4706757-A2 2-(((2,3-DIHYDROBENZO[B][1,4]DIOXAN-5-YL)PIPERIDIN-1-YL)METHYL)-1-((OXETAN-2-YL)METHYL)-1H-BENZO[D]IMIDAZOLE-6-CARBOXYLIC ACID DERIVATIVES AND SIMILAR COMPOUNDS AS GLP-1 MODULATORS FOR THE TREATMENT OF DIABETES Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2026-03-11 EP disclosed
EP-4209490-B1 2-(((2,3-DIHYDROBENZO[B][1,4]DIOXAN-5-YL)PIPERIDIN-1-YL)METHYL)-1-((OXETAN-2-YL)METHYL)-1H-BENZO[D]IMIDAZOLE-6-CARBOXYLIC ACID DERIVATIVES AND SIMILAR COMPOUNDS AS GLP-1 MODULATORS FOR THE TREATMENT OF DIABETES JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN) 2026-01-28 EP disclosed
US-12473279-B2 Fused imidazole derivative, preparation method therefor, and medical use thereof JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2025-11-18 US disclosed
US-12459937-B2 Fused imidazole derivative, preparation method therefor, and medical use thereof JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2025-11-04 US disclosed
US-20250282773-A1 FUSED IMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2025-09-11 US disclosed
US-20250243195-A1 FUSED IMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2025-07-31 US disclosed
US-6136831-A ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL AGENTS, ENZYME INHIBITORS GRELAN PHARMACEUTICAL CO., LTD. (JP) 2000-10-24 US disclosed
EP-1006114-A1 PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM Grelan Pharmaceutical Co., Ltd. (JP) 2000-06-07 EP disclosed
US-6071962-A IN TOPICAL APPLICATIONS TO TREAT VARIOUS SKIN CONDITIONS ATTRIBUTED TO, ACCOMPANIED BY OR EXACERBATED BY ABNORMAL DESQUAMATION INCLUDING DRY SKIN, ICHTHYOSIS, PALMAR AND PLANTAR HYPERKERATOSES, DANDRUFF, LICHEN SIMPLEX CHRONICUS AVON PRODUCTS, INC. (US) 2000-06-06 US disclosed
US-5847003-A Oxa acids and related compounds for treating skin conditions AVON PRODUCTS, INC. (US) 1998-12-08 US disclosed
US-5834513-A TOPICAL COMPOSITION FOR TREATING SKIN CONDITIONS CHARACTERIZED BY ABNORMAL DESQUAMATION AVON PRODUCTS, INC. (US) 1998-11-10 US disclosed
US-5264611-A Process for preparing trans-β-aroylacrylic ester KANEGAFUCHI KAGAKU KABUSHIKI KAISHA (JP) 1993-11-23 US disclosed
EP-0494620-A2 Process for preparing trans-beta-aroylacrylic ester KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1992-07-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12459937-B2 Fused imidazole derivative, preparation method therefor, and medical use thereof GLP1R, GIPR, VIP ALDH1A1 1793/4885RECQL 3809/4885THRB 1362/4885
US-12473279-B2 Fused imidazole derivative, preparation method therefor, and medical use thereof GLP1R, GIPR, VIP ALDH1A1 1793/4885RECQL 3809/4885THRB 1362/4885
US-20250282773-A1 FUSED IMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF GLP1R, GIPR, VIP ALDH1A1 1793/4885RECQL 3809/4885THRB 1362/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR ALDH1A1 4757/4885RECQL 3092/4885THRB 4490/4885
US-20250243195-A1 FUSED IMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF GLP1R, GIPR, VIP ALDH1A1 1793/4885RECQL 3809/4885THRB 1362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.