Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 8/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852086 | 0.85 | ITGB3 (0.53) | LMNAITGB3ITGA2BMAPTNPC1 | |
| SCHEMBL2854478 | 0.83 | ITGB3 (0.46) | LMNAITGB3ITGA2BMAPTNPC1 | |
| SCHEMBL2858063 | 0.78 | MAPT (0.57) | LMNAMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2860983 | 0.76 | MAPT (0.49) | LMNAITGB3ITGA2BMAPTNPC1 | |
| SCHEMBL2854032 | 0.74 | MAPT (0.43) | ITGB3ITGA2BMAPTNPC1RAB9A | |
| SCHEMBL2854457 | 0.73 | CYP3A4 (0.43) | MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2854401 | 0.73 | RAB9A (0.46) | LMNAMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2856949 | 0.72 | LPAR1 (0.48) | LMNAMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2850038 | 0.72 | MAPT (0.46) | LMNAMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2856094 | 0.72 | MAPT (0.42) | ITGB3ITGA2BMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |