Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP7 | P09237 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741349 | 0.78 | HTT (0.61) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14018388 | 0.77 | PTGS2 (0.59) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1020708 | 0.75 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2LPAR1LPAR5 | |
| SCHEMBL4592282 | 0.75 | HTT (0.70) | FFAR1MMP2MMP7MMP14ALDH1A1 | |
| SCHEMBL16621783 | 0.74 | HTT (0.56) | ALDH1A1SMN1; SMN2LPAR1LPAR5 | |
| SCHEMBL16621785 | 0.74 | HTT (0.70) | FFAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL270706 | 0.74 | MMP2 (0.77) | MMP2MMP7MMP14ALDH1A1POLB | |
| SCHEMBL7690257 | 0.74 | ALDH1A1 (0.59) | MMP14ALDH1A1POLBSMN1; SMN2LPAR1 | |
| SCHEMBL8623496 | 0.74 | FFAR1 (0.71) | FFAR1LPAR1LPAR5PPARG | |
| SCHEMBL8746017 | 0.73 | LPAR1 (0.70) | ALDH1A1SMN1; SMN2LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108059607-B | Sulfonylacetic acid or sulfonyl acetic acid derivative, and pharmaceutical composition, preparation method and application thereof | 中国科学院上海药物研究所 | 2020-11-17 | — | — | CN | disclosed |