Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.51 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.51 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PDE6D | O43924 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411964 | 1.00 | PARP1 (0.51) | PARP1PKN1PKN2ALDH1A1KDM4E | |
| SCHEMBL29412017 | 0.92 | PKN1 (0.56) | PARP1PKN1PKN2ALDH1A1PDE6D | |
| SCHEMBL28487665 | 0.92 | PKN1 (0.56) | PARP1PKN1PKN2ALDH1A1PDE6D | |
| SCHEMBL29412060 | 0.90 | PKN1 (0.54) | PARP1PKN1PKN2ALDH1A1KDM4E | |
| SCHEMBL28478408 | 0.90 | ALDH1A1 (0.58) | PARP1PKN1PKN2ALDH1A1PDE6D | |
| SCHEMBL28478067 | 0.89 | ALDH1A1 (0.48) | PARP1PKN1PKN2ALDH1A1KDM4E | |
| SCHEMBL29412051 | 0.89 | ALDH1A1 (0.48) | PARP1PKN1PKN2ALDH1A1KDM4E | |
| SCHEMBL29411959 | 0.87 | PARP1 (0.48) | PARP1PKN1PKN2KDM4ENPSR1 | |
| SCHEMBL28486407 | 0.87 | PARP1 (0.48) | PARP1PKN1PKN2KDM4ENPSR1 | |
| SCHEMBL28484153 | 0.85 | CFTR (0.50) | PARP1PKN1PKN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978301-B | Benzimidazole compound with endothelial lipase inhibition effect and application thereof | 盐城师范学院 | 2022-08-02 | — | — | CN | disclosed |
| CN-111978301-A | Benzimidazole compound with endothelial lipase inhibition effect and application thereof | 盐城师范学院 | 2020-11-24 | — | — | CN | disclosed |