SCHEMBL28484203

SCHEMBL28484203

CC1(C)OB(c2ccc(-n3cccc3)cc2)OC1(C)C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 12/20 0.55
LIPG Q9Y5X9 12/20 0.55
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
CA12 O43570 1/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
F11 P03951 1/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
P4HB P07237 1/20 0.40
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL228212 0.79 LPL (0.71) LPLLIPGCA1CA2CA9
SCHEMBL2551536 0.78 LMNA (0.49) LPLLIPGCA1CA2CA9
SCHEMBL20401802 0.78 LIPG (0.56) LPLLIPGCA1CA2CA9
SCHEMBL29348327 0.78 LIPG (0.51) LPLLIPGCA1CA2CA9
SCHEMBL2756334 0.76 LIPG (0.53) LPLLIPGCA1CA2CA9
SCHEMBL2016964 0.75 NOTUM (0.49) LPLLIPGCA1CA2CA9
SCHEMBL26921559 0.75 JAK2 (0.38) LPLLIPGKDM4EGAANPSR1
SCHEMBL15986832 0.74 LPL (0.50) LPLLIPGCA1CA2CA9
SCHEMBL28365135 0.74 LIPG (0.59) LPLLIPGCA1CA2CA9
SCHEMBL15011969 0.74 LPL (0.50) LPLLIPGCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025227032-A1 METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES REMIX THERAPEUTICS INC. (US) 2025-10-30 WO disclosed
CN-112020500-A Aminopyridine derivatives as inhibitors of phosphatidylinositol phosphokinase 拉文纳制药公司 2020-12-01 CN disclosed