Sugi Predict

Sugi Predict / Compounds / SCHEMBL2016964

SCHEMBL2016964

SCHEMBL2016964

CC1(C)OB(c2ccc(-n3cccn3)cc2)OC1(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOTUM Q6P988 1/20 0.49
▸ LPL P06858 12/20 0.47
▸ LIPG Q9Y5X9 12/20 0.47
▸ KDM4E B2RXH2 1/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ MAPK1 P28482 1/20 0.45
▸ CHRNA7 P36544 1/20 0.40
▸ CHRNA10 Q9GZZ6 1/20 0.40
▸ CHRNA9 Q9UGM1 1/20 0.40
▸ CA1 P00915 2/20 0.38
▸ CA2 P00918 2/20 0.38
▸ CA9 Q16790 2/20 0.38
▸ CA12 O43570 1/20 0.38
▸ CA3 P07451 1/20 0.38
▸ CA4 P22748 1/20 0.38
▸ CA6 P23280 1/20 0.38
▸ CA5A P35218 1/20 0.38
▸ CA7 P43166 1/20 0.38
▸ CA14 Q9ULX7 1/20 0.38
▸ CA5B Q9Y2D0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16322408 0.96 LIPG (0.55) NOTUMLPLLIPGKDM4EALDH1A1
SCHEMBL382745 0.84 LPL (0.42) NOTUMLPLLIPGKDM4EALDH1A1
SCHEMBL25100974 0.83 LPL (0.43) NOTUMLPLLIPGKDM4EALDH1A1
SCHEMBL22567197 0.82 LPL (0.40) NOTUMLPLLIPGKDM4EALDH1A1
SCHEMBL30884952 0.80 KDM4E (0.38) NOTUMLPLLIPGKDM4EALDH1A1
SCHEMBL27096635 0.80 KDM4E (0.38) NOTUMLPLLIPGKDM4EALDH1A1
SCHEMBL860013 0.80 LMNA (0.46) LPLLIPGKDM4EALDH1A1CHRNA7
SCHEMBL30345421 0.79 TDO2 (0.33) NOTUMLPLLIPGKDM4EALDH1A1
SCHEMBL13310594 0.79 NOTUM (0.40) NOTUMKDM4EALDH1A1MAPK1CHRNA7
SCHEMBL26920637 0.79 NOTUM (0.46) NOTUMKDM4EALDH1A1MAPK1CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4539840-A1 KINASE MODULATORS AND METHODS OF USE THEREOF Neuron23, Inc. (US) 2025-04-23 — — EP disclosed
US-20250115630-A1 METAL COMPLEXES UDC IRELAND LTD (IE) 2025-04-10 — — US disclosed
US-12180233-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-12-31 — — US disclosed
WO-2023244788-A9 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2024-09-12 — — WO disclosed
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF SUNDANCE BIOSCIENCES, INC. 2024-01-25 — — US disclosed
WO-2023244788-A1 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2023-12-21 — — WO disclosed
EP-3752512-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-03-01 — — EP disclosed
EP-3752512-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-03-01 — — EP disclosed
US-20220289778-A1 METAL COMPLEXES UDC IRELAND LIMITED (IE) 2022-09-15 — — US disclosed
US-11384055-B2 Glycolate oxidase inhibitors for the treatment of disease BIOMARIN PHARMACEUTICAL INC. (US) 2022-07-12 — — US disclosed
US-20150182513-A1 N-Link Hydroxamic Acid Derivatives Useful As Antibacterial Agents PFIZER INC. (US) 2015-07-02 — — US disclosed
US-9018384-B2 N-link hydroxamic acid derivatives useful as antibacterial agents PFIZER INC. (US) 2015-04-28 — — US disclosed
US-20140343031-A1 N-Link Hydroxamic Acid Derivatives Useful As Antibacterial Agents PFIZER INC. (US) 2014-11-20 — — US disclosed
EP-2512474-B1 N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS PFIZER (US) 2014-11-05 — — EP disclosed
US-8846933-B2 N-link hydroxamic acid derivatives useful as antibacterial agents PFIZER INC. (US) 2014-09-30 — — US disclosed
US-20140128363-A1 N-Link Hydroxamic Acid Derivatives Useful As Antibacterial Agents PFIZER (US) 2014-05-08 — — US disclosed
US-8664401-B2 N-linked hydroxamic acid derivatives useful as antibacterial agents PFIZER INC. (US) 2014-03-04 — — US disclosed
EP-2512474-A1 N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS Pfizer Inc. (US) 2012-10-24 — — EP disclosed
US-20120258948-A1 N-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents PFIZER INC. 2012-10-11 — — US disclosed
WO-2011073845-A1 N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS PFIZER INC. (US) 2011-06-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150182513-A1 N-Link Hydroxamic Acid Derivatives Useful As Antibacterial Agents LPXN, NAAA, AGXT NOTUM 3235/4885LPL 1201/4885LIPG 1011/4885
US-20120258948-A1 N-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents LPXN, LCT, HAX1 NOTUM 3927/4885LPL 541/4885LIPG 482/4885
US-12180233-B2 Metal complexes IMMT, MCU, SOD1 NOTUM 2327/4885LPL 3959/4885LIPG 3702/4885
US-20140128363-A1 N-Link Hydroxamic Acid Derivatives Useful As Antibacterial Agents LPXN, NAAA, AGXT NOTUM 3235/4885LPL 1201/4885LIPG 1011/4885
US-20250115630-A1 METAL COMPLEXES IMMT, MCU, SOD1 NOTUM 2327/4885LPL 3959/4885LIPG 3702/4885
US-11384055-B2 Glycolate oxidase inhibitors for the treatment of disease XDH, PNPO, AGXT NOTUM 643/4885LPL 658/4885LIPG 485/4885
US-20220289778-A1 METAL COMPLEXES IMMT, MCU, SOD1 NOTUM 2327/4885LPL 3959/4885LIPG 3702/4885
US-20140343031-A1 N-Link Hydroxamic Acid Derivatives Useful As Antibacterial Agents LPXN, NAAA, AGXT NOTUM 3235/4885LPL 1201/4885LIPG 1011/4885
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF TYK2, JAK1, JAK3 NOTUM 2856/4885LPL 4811/4885LIPG 4222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.