Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 11/20 | 0.54 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21206426 | 1.00 | BCHE (0.54) | BCHEHTR4TMEM97CARM1PRMT6 | |
| SCHEMBL4024133 | 0.93 | BCHE (0.62) | BCHEHTR4TMEM97CARM1PRMT6 | |
| SCHEMBL21198787 | 0.86 | BCHE (0.58) | BCHEHTR4TMEM97CARM1PRMT6 | |
| SCHEMBL21198788 | 0.86 | BCHE (0.58) | BCHEHTR4TMEM97CARM1PRMT6 | |
| SCHEMBL28489343 | 0.85 | BCHE (0.57) | BCHEHTR4TMEM97CARM1PRMT6 | |
| SCHEMBL28489345 | 0.85 | BCHE (0.57) | BCHEHTR4TMEM97CARM1PRMT6 | |
| SCHEMBL9058678 | 0.83 | HTR4 (0.48) | BCHEHTR4TMEM97SIGMAR1HRH3 | |
| Lithium Ion SCHEMBL29789468 | 0.83 | BCHE (0.55) | BCHETMEM97CARM1PRMT6SIGMAR1 | |
| SCHEMBL1787933 | 0.82 | CHRNB2 (0.50) | BCHETMEM97CARM1PRMT6SIGMAR1 | |
| SCHEMBL8480400 | 0.81 | EGFR (0.63) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868061-A | 2, 8-diacyl-2, 8-diazaspiro [5.5] undecane compounds useful as immunomodulators | 百时美施贵宝公司 | 2020-10-30 | — | — | CN | disclosed |