Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 6/20 | 0.45 |
| ▸ | NOS1 | P29475 | 4/20 | 0.45 |
| ▸ | NOS3 | P29474 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 4/20 | 0.42 |
| ▸ | ARG1 | P05089 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21335953 | 0.85 | GSR (0.47) | GSRNOS2NOS1NOS3CYP1A2 | |
| SCHEMBL29485083 | 0.84 | GSR (0.61) | GSRNOS2NOS1NOS3CYP1A2 | |
| SCHEMBL359142 | 0.83 | GSR (0.55) | GSRCYP1A2BLMKMT2AARG2 | |
| SCHEMBL2263990 | 0.83 | GSR (0.55) | GSRCYP1A2BLMKMT2AARG2 | |
| SCHEMBL2263983 | 0.83 | GSR (0.55) | GSRCYP1A2BLMKMT2AARG2 | |
| SCHEMBL10187368 | 0.81 | GSR (0.52) | GSRNOS2NOS1NOS3CYP1A2 | |
| SCHEMBL10187360 | 0.80 | NOS2 (0.45) | GSRNOS2NOS1NOS3CYP1A2 | |
| SCHEMBL25227671 | 0.80 | GSR (0.52) | GSRNOS2NOS1NOS3CYP1A2 | |
| SCHEMBL9362560 | 0.80 | GRIK1 (0.56) | GSRTSHRARG2ARG1GRIK1 | |
| SCHEMBL10285774 | 0.80 | NOD1 (0.52) | GSRNOS1ARG2ARG1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116121275-B | Acquisition and application of liver targeting novel adeno-associated virus | 北京三诺佳邑生物技术有限责任公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-116121274-B | Acquisition and application of liver targeting novel adeno-associated virus | 北京三诺佳邑生物技术有限责任公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-115927398-B | Acquisition and application of liver targeting novel adeno-associated virus | 北京三诺佳邑生物技术有限责任公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-115960921-B | Acquisition and application of liver targeting novel adeno-associated virus | 北京三诺佳邑生物技术有限责任公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-116121274-A | Acquisition and application of liver targeting novel adeno-associated virus | 北京三诺佳邑生物技术有限责任公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-116121275-A | Acquisition and application of liver targeting novel adeno-associated virus | 北京三诺佳邑生物技术有限责任公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-115960921-A | Acquisition and application of novel liver-targeted adeno-associated viruses | 舒泰神（北京）生物制药股份有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115927398-A | Acquisition and application of novel liver-targeted adeno-associated viruses | 舒泰神（北京）生物制药股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-111876432-B | Acquisition and application of novel liver-targeted adeno-associated viruses | 舒泰神（北京）生物制药股份有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-111876432-A | Acquisition and application of novel liver-targeted adeno-associated viruses | 舒泰神（北京）生物制药股份有限公司 | 2020-11-03 | — | — | CN | disclosed |