SCHEMBL359142

SCHEMBL359142

N[C@@H](CCCCNCCC(=O)O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.55
GRM8 O00222 2/20 0.55
GRM6 O15303 2/20 0.55
GRM7 Q14831 2/20 0.55
GRM4 Q14833 2/20 0.55
GRIN2D O15399 1/20 0.55
GRIN3B O60391 1/20 0.55
CYP1A2 P05177 1/20 0.55
GRIK1 P39086 1/20 0.55
GRM5 P41594 1/20 0.55
GRIA1 P42261 1/20 0.55
GRIA2 P42262 1/20 0.55
GRIA3 P42263 1/20 0.55
SLC1A3 P43003 1/20 0.55
SLC1A2 P43004 1/20 0.55
SLC1A1 P43005 1/20 0.55
GRIA4 P48058 1/20 0.55
GRIN1 Q05586 1/20 0.55
GRIN2A Q12879 1/20 0.55
GRIK2 Q13002 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2263983 1.00 GSR (0.55) GSRGRM8GRM6GRM7GRM4
SCHEMBL2263990 1.00 GSR (0.55) GSRGRM8GRM6GRM7GRM4
SCHEMBL29741400 0.94 GSR (0.57) GSRGRM8GRM6GRM7GRM4
SCHEMBL29485083 0.90 GSR (0.61) GSRGRM8GRM6GRM7GRM4
SCHEMBL28717409 0.87 ARG2 (0.50) GSRGRM8GRM6GRM7GRM4
SCHEMBL2548650 0.87 GSR (0.53) GSRGRM8GRM6GRM7GRM4
SCHEMBL43621 0.87 GSR (0.53) GSRGRM8GRM6GRM7GRM4
Water SCHEMBL380639 0.85 GSR (0.52) GSRGRM8GRM6GRM7GRM4
SCHEMBL448753 0.83 GSR (0.77) GSRCYP1A2ARG2ARG1ALOX15
SCHEMBL31612943 0.83 GSR (0.53) GSRGRM8GRM6GRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119317362-A Pet food compositions and methods for reducing metabolites associated with protein spoilage in felines 希尔氏宠物营养品公司 2025-01-14 CN claimed
EP-4391825-A1 PET FOOD COMPOSITIONS AND METHOD FOR REDUCING METABOLITES ASSOCIATED WITH PROTEIN PUTREFACTION IN A FELINE Hill's Pet Nutrition, Inc. (US) 2024-07-03 EP claimed
US-20230404951-A1 Pet Food Compositions HILL'S PET NUTRITION, INC. (US) 2023-12-21 US claimed
WO-2023244712-A1 PET FOOD COMPOSITIONS AND METHOD FOR REDUCING METABOLITES ASSOCIATED WITH PROTEIN PUTREFACTION IN A FELINE HILL'S PET NUTRITION, INC. (US) 2023-12-21 WO claimed
US-20180340926-A1 METHODS FOR IMPROVING DIABETES MANAGEMENT JOURNEY BIOSCIENCES, LLC 2018-11-29 US claimed
EP-3341720-A1 METHODS FOR IMPROVING DIABETES MANAGEMENT PreventAGE Healthcare, LLC (US) 2018-07-04 EP claimed
WO-2017039743-A1 METHODS FOR IMPROVING DIABETES MANAGEMENT PREVENTAGE HEALTH CARE LLC (US) 2017-03-09 WO claimed
US-20140154257-A1 Materials and methods for diagnosing and treating asthma and dietary Fru-AGEs related disorders including auto-immune and other diseases found to be associated with elevated RAGE. The specification describes methods to identify and make dietary derived advanced glycation end-products, known as Fru-AGEs, Fru-AGE-haptens, and Fru-AGE immune complexes, and to make monoclonal and polyclonal antibodies to this plurality of bio-molecules for use in immunoassays and for use as therapeutic agents DECHRISTOPHER LUANNE ROBALO (US) 2014-06-05 US claimed
US-20050124071-A1 Methods and compositions for diagnosing musculoskeletal, arthritic and joint disorders by biomarker dating NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-06-09 US claimed
WO-2005033705-A1 METHODS AND COMPOSITIONS FOR DIAGNOSING MUSCULOSKELETAL, ARTHRITIC AND JOINT DISORDERS BY BIOMARKER DATING DUKE UNIVERSITY (US) 2005-04-14 WO claimed
US-20260022384-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF OSPEDALE SAN RAFFAELE S.R.L. (IT) 2026-01-22 US disclosed
US-20250375505-A1 COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM UNIV CALIFORNIA (US) 2025-12-11 US disclosed
WO-2025051692-A1 DETOXIFYING PEPTIDE REGENTIS PHARMA (FR) 2025-03-13 WO disclosed
CN-119317362-A Pet food compositions and methods for reducing metabolites associated with protein spoilage in felines 希尔氏宠物营养品公司 2025-01-14 CN disclosed
US-20240293472-A1 Bee Product Extracts, Methods of Production, and Uses Thereof QUANTUM TECHNOLOGIES LIMITED (NZ) 2024-09-05 US disclosed
US-6890754-B2 Epidermis/dermis equivalents and aged skin equivalents shaped therefrom L'OREAL (FR) 2005-05-10 US disclosed
WO-2005033705-A1 METHODS AND COMPOSITIONS FOR DIAGNOSING MUSCULOSKELETAL, ARTHRITIC AND JOINT DISORDERS BY BIOMARKER DATING DUKE UNIVERSITY (US) 2005-04-14 WO disclosed
US-20040052772-A1 Novel epidermis/dermis equivalents and aged skin equivalents shaped therefrom SOCIETE L'OREAL S.A. 2004-03-18 US disclosed
EP-1317765-A2 AUTOMATED IDENTIFICATION OF PEPTIDES Oxford GlycoSciences (UK) Limited (GB) 2003-06-11 EP disclosed
WO-2002021139-A2 AUTOMATED IDENTIFICATION OF PEPTIDES OXFORD GLYCOSCIENCES (UK) LTD. (GB) 2002-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250375505-A1 COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM CYP27A1, LIPC, CYP46A1 GSR 269/4885GRM8 1972/4885GRM6 956/4885
US-20140154257-A1 Materials and methods for diagnosing and treating asthma and dietary Fru-AGEs related disorders including auto-immune and other diseases found to be associated with elevated RAGE. The specification describes methods to identify and make dietary derived advanced glycation end-products, known as Fru-AGEs, Fru-AGE-haptens, and Fru-AGE immune complexes, and to make monoclonal and polyclonal antibodies to this plurality of bio-molecules for use in immunoassays and for use as therapeutic agents AGER, FABP2, FCER2 GSR 1713/4885GRM8 804/4885GRM6 1577/4885
US-20260022384-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF ASNS, AARS1, NARS1 GSR 2917/4885GRM8 4765/4885GRM6 4785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.