Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28489310 | 0.76 | OPRM1 (0.44) | OPRM1SLC6A2SLC6A4SLC6A3OPRL1 | |
| SCHEMBL4120433 | 0.76 | OPRM1 (0.60) | OPRM1SLC6A2SLC6A4SLC6A3OPRL1 | |
| SCHEMBL28488803 | 0.74 | SLC6A2 (0.42) | OPRM1SLC6A2SLC6A4SLC6A3OPRL1 | |
| SCHEMBL8135217 | 0.69 | SLC6A2 (0.53) | OPRM1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL27699362 | 0.68 | OPRL1 (0.54) | OPRM1OPRL1OPRK1MEN1ALDH1A1 | |
| SCHEMBL1919144 | 0.68 | SLC6A2 (0.56) | OPRM1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL6543165 | 0.68 | SLC6A2 (0.52) | OPRM1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL28285338 | 0.68 | OPRM1 (0.40) | OPRM1SLC6A2SLC6A4SLC6A3OPRD1 | |
| SCHEMBL7961014 | 0.68 | SLC6A2 (0.46) | OPRM1SLC6A2SLC6A4SLC6A3OPRL1 | |
| SCHEMBL19470000 | 0.67 | OPRM1 (0.44) | OPRM1SLC6A2SLC6A4LMNAOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761883-B | 4-carbamate-cinnamamide-4-benzyl piperidine compound and preparation method and application thereof | 南阳师范学院 | 2020-11-03 | — | — | CN | disclosed |