Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28489310 | 0.75 | OPRM1 (0.44) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL28285338 | 0.74 | OPRM1 (0.40) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL28486298 | 0.74 | OPRM1 (0.40) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL4120433 | 0.74 | OPRM1 (0.60) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL2183965 | 0.73 | OPRM1 (0.42) | SLC6A2SLC6A4KMT2AMEN1OPRM1 | |
| SCHEMBL19470000 | 0.71 | OPRM1 (0.44) | SLC6A2SLC6A4KMT2AMEN1NPC1 | |
| SCHEMBL5592301 | 0.70 | CTSD (0.37) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL16826119 | 0.70 | TACR1 (0.39) | SLC6A2SLC6A3KMT2ATDP1OPRM1 | |
| SCHEMBL28274626 | 0.69 | L3MBTL1 (0.38) | OPRM1SIGMAR1 | |
| SCHEMBL1919144 | 0.69 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761883-B | 4-carbamate-cinnamamide-4-benzyl piperidine compound and preparation method and application thereof | 南阳师范学院 | 2020-11-03 | — | — | CN | disclosed |