Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 13/20 | 0.54 |
| ▸ | PDE4A | P27815 | 5/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | QDPR | P09417 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479794 | 0.97 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL28487133 | 0.91 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL28491678 | 0.83 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DHPGD | |
| Bicarbonate SCHEMBL9574485 | 0.83 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DQDPR | |
| SCHEMBL28479252 | 0.81 | ALDH1A1 (0.49) | PDE4BHPGDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9188312 | 0.81 | NR3C1 (0.60) | PDE4BPDE4APDE4CPDE4DQDPR | |
| SCHEMBL28487589 | 0.79 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4DHPGD | |
| Formic Acid SCHEMBL28266826 | 0.79 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4DQDPR | |
| SCHEMBL8320004 | 0.79 | POLB (0.63) | HPGDHTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL9574528 | 0.78 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4DQDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954664-A | Cystic fibrosis transmembrane conductance regulator and methods of use | 艾伯维海外有限公司 | 2020-11-17 | — | — | CN | disclosed |