Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 2/20 | 0.38 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479794 | 0.82 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL28486348 | 0.79 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL28491679 | 0.76 | PDGFRB (0.43) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL28487133 | 0.76 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL28479970 | 0.76 | L3MBTL1 (0.54) | HPGDHTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL28479820 | 0.75 | KMT2A (0.45) | HPGDHTTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL29267402 | 0.70 | PTAFR (0.62) | KMT2AMAPTTSHRPTAFRTUBB4A | |
| SCHEMBL14641983 | 0.70 | ERN1 (0.43) | PDE4BPDE4APDE4CPDE4DTDP1 | |
| Bicarbonate SCHEMBL9574485 | 0.70 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DQDPR | |
| SCHEMBL20789986 | 0.70 | PDGFRB (0.42) | PDE4BPDE4APDE4CPDE4DPTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954664-A | Cystic fibrosis transmembrane conductance regulator and methods of use | 艾伯维海外有限公司 | 2020-11-17 | — | — | CN | disclosed |