Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863128 | 0.87 | TAAR1 (0.47) | LMNACNR1TAAR1SCD5NPC1 | |
| SCHEMBL2852519 | 0.86 | TAAR1 (0.59) | TAAR1MEN1KMT2ANPC1GAA | |
| SCHEMBL2854712 | 0.86 | TAAR1 (0.54) | CNR1TAAR1MEN1KMT2ANPC1 | |
| SCHEMBL2857813 | 0.84 | TAAR1 (0.55) | CNR1TAAR1MEN1KMT2ANPC1 | |
| SCHEMBL2852630 | 0.83 | TAAR1 (0.52) | LMNATAAR1KDM4ENPC1GAA | |
| SCHEMBL2859353 | 0.81 | TAAR1 (0.66) | LMNACNR1TAAR1MEN1KMT2A | |
| SCHEMBL2852329 | 0.81 | TAAR1 (0.49) | TAAR1KDM4EMEN1KMT2ATRPV1 | |
| SCHEMBL2848393 | 0.80 | TAAR1 (0.48) | CNR1TAAR1SCD5KDM4EKMT2A | |
| SCHEMBL2860106 | 0.77 | KLKB1 (0.52) | SCD5NPC1RAB9A | |
| SCHEMBL2850420 | 0.76 | TAAR1 (0.49) | LMNACNR1TAAR1SCD5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |