Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852519 | 0.89 | TAAR1 (0.59) | TAAR1ALDH1A1SMN1; SMN2KLKB1NPC1 | |
| SCHEMBL2854712 | 0.86 | TAAR1 (0.54) | TAAR1ALDH1A1SMN1; SMN2KLKB1NPC1 | |
| SCHEMBL2859353 | 0.86 | TAAR1 (0.66) | TAAR1ALDH1A1SMN1; SMN2NPC1GAA | |
| SCHEMBL2863128 | 0.83 | TAAR1 (0.47) | TAAR1NPC1GAARAB9APOLB | |
| SCHEMBL2852630 | 0.83 | TAAR1 (0.52) | TAAR1ALDH1A1NPC1GAARAB9A | |
| SCHEMBL2853080 | 0.82 | LMNA (0.50) | ALDH1A1SMN1; SMN2KLKB1NPC1RAB9A | |
| SCHEMBL2857813 | 0.82 | TAAR1 (0.55) | TAAR1KLKB1NPC1GAARAB9A | |
| SCHEMBL2848393 | 0.82 | TAAR1 (0.48) | TAAR1ALDH1A1SMN1; SMN2KLKB1NPC1 | |
| SCHEMBL2858437 | 0.81 | TAAR1 (0.42) | TAAR1ALDH1A1SMN1; SMN2NPC1GAA | |
| SCHEMBL2860106 | 0.81 | KLKB1 (0.52) | ALDH1A1SMN1; SMN2KLKB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |