Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.46 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.46 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | TCF4 | P15884 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852519 | 0.93 | TAAR1 (0.59) | TAAR1NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL2859353 | 0.90 | TAAR1 (0.66) | TAAR1NPC1RAB9AGAALMNA | |
| SCHEMBL2863128 | 0.89 | TAAR1 (0.47) | TAAR1NPC1RAB9AGAALMNA | |
| SCHEMBL2848515 | 0.89 | LMNA (0.50) | NPC1RAB9ALMNAPTGER4TCF4 | |
| SCHEMBL2848393 | 0.86 | TAAR1 (0.48) | TAAR1NPC1RAB9AGAAMAPT | |
| SCHEMBL2854712 | 0.84 | TAAR1 (0.54) | TAAR1NPC1RAB9AGAAPLAAT3 | |
| SCHEMBL2852329 | 0.83 | TAAR1 (0.49) | TAAR1NPC1RAB9AGAAMAPT | |
| SCHEMBL2848658 | 0.83 | LMNA (0.46) | TAAR1NPC1RAB9AGAALMNA | |
| SCHEMBL2857813 | 0.82 | TAAR1 (0.55) | TAAR1NPC1RAB9AGAAMAPT | |
| SCHEMBL2850420 | 0.82 | TAAR1 (0.49) | TAAR1NPC1RAB9AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |