Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 3/20 | 0.34 |
| ▸ | PGK2 | P07205 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL214829 | 0.87 | ALOX15 (0.60) | ALOX15CA2CA4CA5APTPN1 | |
| Ammonia Solution, Strong SCHEMBL28553518 | 0.82 | ALOX15 (0.94) | ALOX15MAPTPTGS1PTGS2KDM4E | |
| Perchlorate SCHEMBL30006851 | 0.76 | ALOX15 (0.71) | ALOX15MAPTPTGS1KDM4ENPC1 | |
| Toluene SCHEMBL29091429 | 0.71 | ALOX15 (0.71) | ALOX15CA2MAPTKDM4ENPC1 | |
| Naphthalene SCHEMBL3796240 | 0.64 | CYP2A6 (0.57) | CA2CA4CA5APTPN1PGK1 | |
| Naphthalene SCHEMBL19062554 | 0.64 | CYP2A6 (0.57) | CA2CA4CA5APTPN1PGK1 | |
| Phosphoric Acid SCHEMBL4104685 | 0.64 | CA2 (0.50) | ALOX15CA2CA4CA5APTPN1 | |
| Triphenylene SCHEMBL1756536 | 0.64 | CA2 (0.50) | ALOX15CA2CA4CA5APTPN1 | |
| Naphthalene SCHEMBL1680172 | 0.64 | CYP2A6 (0.57) | CA2CA4CA5APTPN1PGK1 | |
| Naphthalene SCHEMBL30445823 | 0.64 | CYP2A6 (0.57) | CA2CA4CA5APTPN1PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118207553-A | Phosphated indolizine, derivative thereof, preparation method and application thereof | 上海陶术生物科技有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-118207553-A | Phosphated indolizine, derivative thereof, preparation method and application thereof | 上海陶术生物科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-118207553-A | Phosphated indolizine, derivative thereof, preparation method and application thereof | 上海陶术生物科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-118207553-A | Phosphated indolizine, derivative thereof, preparation method and application thereof | 上海陶术生物科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-111868146-A | Composite materials comprising mechanical ligands | 纳诺科尔有限公司 | 2020-10-30 | — | — | CN | disclosed |