Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28488673 | 0.87 | GPR139 (0.42) | GPR139ALDH1A1MEN1KMT2APKM | |
| SCHEMBL30778076 | 0.84 | GPR139 (0.51) | GPR139ALDH1A1MEN1KMT2APKM | |
| SCHEMBL17950532 | 0.83 | NPC1 (0.44) | GPR139ALDH1A1MEN1KMT2AHDAC3 | |
| SCHEMBL17950668 | 0.77 | GPR139 (0.52) | GPR139ALDH1A1MEN1KMT2APKM | |
| SCHEMBL17950675 | 0.76 | PKM (0.46) | GPR139MEN1KMT2APKMCTSD | |
| SCHEMBL17950740 | 0.76 | MEN1 (0.68) | ALDH1A1MEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL28488309 | 0.76 | KMT2A (0.45) | ALDH1A1MEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL17150506 | 0.73 | GPR139 (0.47) | GPR139ALDH1A1MEN1KMT2A | |
| SCHEMBL30778050 | 0.72 | GPR139 (0.45) | GPR139MEN1KMT2A | |
| SCHEMBL17950590 | 0.69 | SMN1; SMN2 (0.44) | GPR139ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530037-B | Triazine heterocyclic compound with nematicidal activity and preparation method and application thereof | 华东理工大学 | 2020-12-18 | — | — | CN | disclosed |