Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 known ✓ | Q9NR96 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.59 |
| ▸ | APLNR | P35414 | 1/20 | 0.59 |
| ▸ | CCR6 | P51684 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA3 | P07451 | 3/20 | 0.51 |
| ▸ | CA4 | P22748 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577803 | 0.94 | ACHE (0.75) | ACHEHSD17B10KMT2ARAB9AHSP90AA1 | |
| 4-Nitrotoluene SCHEMBL27415361 | 0.92 | ACHE (0.78) | ACHEHSD17B10KMT2ARAB9AHSP90AA1 | |
| 4-Nitrotoluene SCHEMBL27415359 | 0.92 | ACHE (0.78) | ACHEHSD17B10KMT2ARAB9AHSP90AA1 | |
| SCHEMBL19272432 | 0.87 | ACHE (0.69) | ACHEHSD17B10KMT2ARAB9AHSP90AA1 | |
| 4-Nitrotoluene SCHEMBL8957077 | 0.85 | ACHE (0.72) | ACHEHSD17B10KMT2ARAB9AHSP90AA1 | |
| SCHEMBL11419996 | 0.84 | CA2 (0.67) | ACHEHSD17B10KMT2AGAAPOLB | |
| SCHEMBL3158508 | 0.84 | CA2 (0.67) | ACHEHSD17B10KMT2AGAAPOLB | |
| SCHEMBL11855965 | 0.84 | CA2 (0.67) | ACHEHSD17B10KMT2AGAAPOLB | |
| SCHEMBL22908494 | 0.82 | ACHE (0.75) | ACHEHSD17B10KMT2ARAB9AHSP90AA1 | |
| 4-Nitrotoluene SCHEMBL28795853 | 0.82 | HSD17B10 (0.90) | ACHEHSD17B10KMT2ABCHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109553557-B | Method for synthesizing thiosulfonate compound based on sulfur dioxide insertion strategy | 曲阜师范大学 | 2020-12-01 | — | — | CN | disclosed |