Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51973 | 0.98 | KMT2A (0.34) | KMT2ANPC1RAB9ASLC22A2SLC22A1 | |
| Fluoride SCHEMBL27794969 | 0.96 | KMT2A (0.33) | KMT2ANPC1RAB9ASLC22A2SLC22A1 | |
| Iodide SCHEMBL28651393 | 0.83 | GAA (0.41) | KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL9095823 | 0.81 | GAA (0.42) | KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL29811019 | 0.79 | GAA (0.41) | KMT2AMAPTMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31376364 | 0.79 | GAA (0.41) | KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL30462670 | 0.76 | L3MBTL1 (0.43) | KMT2AMAPT | |
| SCHEMBL27605532 | 0.76 | ALDH1A1 (0.33) | KMT2A | |
| SCHEMBL28311090 | 0.75 | DRD2 (0.38) | KMT2ANPC1RAB9AMAPTMAPK1 | |
| SCHEMBL21181464 | 0.75 | NISCH (0.39) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117363684-A | Method for detecting influence of cigarette smoke on mitochondrial morphology and quantity and application thereof | 江苏中烟工业有限责任公司 | 2024-01-09 | — | — | CN | claimed |
| CN-117771207-A | Drug-loaded nano composite particle and application thereof | 华南师范大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-117363684-A | Method for detecting influence of cigarette smoke on mitochondrial morphology and quantity and application thereof | 江苏中烟工业有限责任公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-117363684-A | Method for detecting influence of cigarette smoke on mitochondrial morphology and quantity and application thereof | 江苏中烟工业有限责任公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-116867508-A | Lectin proteins for the treatment and prevention of neurodegenerative diseases | 联合化学实验室有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-114836386-A | Wnt1 protein-loaded engineered exosome targeting brain tissue and preparation method and application thereof | 电子科技大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-111961213-B | Sequence-controllable supramolecular polymer and preparation method and application thereof | 香港科技大学深圳研究院 | 2022-06-24 | — | — | CN | disclosed |
| CN-113423417-A | Compounds for the treatment of parkinson's disease | 约翰内斯堡威特沃特斯兰德大学 | 2021-09-21 | — | — | CN | disclosed |
| CN-113181210-A | Polyethylene glycol modified two-dimensional nanomaterial and preparation method and application thereof | 南开大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-111956666-B | Polyethylene glycol modified two-dimensional nanomaterial and preparation method and application thereof | 南开大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-111961213-A | Sequence-controllable supramolecular polymer and preparation method and application thereof | 香港科技大学深圳研究院 | 2020-11-20 | — | — | CN | disclosed |
| CN-111956666-A | Polyethylene glycol modified two-dimensional nanomaterial and preparation method and application thereof | 南开大学 | 2020-11-20 | — | — | CN | disclosed |