Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAT2A | P31153 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102988 | 0.80 | KAT2B (0.46) | SMN1; SMN2MAT2ADPP4ALDH1A1KDM4E | |
| SCHEMBL28494811 | 0.79 | MAT2A (0.44) | SMN1; SMN2MAT2ADPP4ALDH1A1KDM4E | |
| SCHEMBL28487663 | 0.74 | MAT2A (0.40) | SMN1; SMN2MAT2ADPP4ALDH1A1KDM4E | |
| SCHEMBL12628808 | 0.73 | KDM4E (0.46) | SMN1; SMN2DPP4ALDH1A1KDM4EMAPT | |
| SCHEMBL28480184 | 0.72 | ALDH1A1 (0.49) | SMN1; SMN2MAT2ADPP4ALDH1A1KDM4E | |
| SCHEMBL28683528 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2DPP4ALDH1A1KDM4EMAPT | |
| SCHEMBL28470339 | 0.71 | SMN1; SMN2 (0.45) | SMN1; SMN2DPP4ALDH1A1KDM4EHTT | |
| SCHEMBL4865308 | 0.70 | SMN1; SMN2 (0.43) | SMN1; SMN2MAT2ADPP4ALDH1A1KDM4E | |
| SCHEMBL29387435 | 0.70 | SMN1; SMN2 (0.43) | SMN1; SMN2MAT2ADPP4ALDH1A1KDM4E | |
| SCHEMBL28222792 | 0.70 | MAT2A (0.40) | SMN1; SMN2MAT2ADPP4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191834-B | Preparation method of benzo-fused N-heterocyclic compound | 中山大学 | 2020-10-16 | — | — | CN | disclosed |