Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SLC11A2 | P49281 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28480184 | 0.76 | ALDH1A1 (0.49) | MAT2ASMN1; SMN2DPP4ALDH1A1KDM4E | |
| SCHEMBL28488134 | 0.75 | MAPK14 (0.47) | MAT2ASMN1; SMN2DPP4ALDH1A1KDM4E | |
| SCHEMBL28487644 | 0.74 | SMN1; SMN2 (0.45) | MAT2ASMN1; SMN2SLC11A2DPP4ALDH1A1 | |
| SCHEMBL28222792 | 0.74 | MAT2A (0.40) | MAT2ASMN1; SMN2DPP4ALDH1A1KDM4E | |
| SCHEMBL28488178 | 0.73 | MAPK14 (0.45) | MAT2ASMN1; SMN2SLC11A2DPP4ALDH1A1 | |
| SCHEMBL28478839 | 0.70 | DPP4 (0.44) | MAT2ASMN1; SMN2SLC11A2DPP4ALDH1A1 | |
| SCHEMBL28462043 | 0.66 | KDM4E (0.39) | SMN1; SMN2SLC11A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL680518 | 0.65 | MAT2A (0.46) | MAT2ASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL12628808 | 0.65 | KDM4E (0.46) | SMN1; SMN2DPP4ALDH1A1KDM4ELMNA | |
| Acrylic Acid Methyl Ester SCHEMBL31473027 | 0.65 | ALDH1A1 (0.41) | MAT2ASMN1; SMN2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191834-B | Preparation method of benzo-fused N-heterocyclic compound | 中山大学 | 2020-10-16 | — | — | CN | disclosed |