Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | MAT2A | P31153 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28480184 | 0.82 | ALDH1A1 (0.49) | DPP4MAT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28478839 | 0.81 | DPP4 (0.44) | MAPK14DPP4MAT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28222792 | 0.75 | MAT2A (0.40) | DPP4MAT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28487663 | 0.73 | MAT2A (0.40) | MAPK14DPP4MAT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28494811 | 0.72 | MAT2A (0.44) | MAPK14DPP4MAT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28487644 | 0.70 | SMN1; SMN2 (0.45) | MAPK14DPP4MAT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12628808 | 0.69 | KDM4E (0.46) | DPP4SMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL18589085 | 0.68 | GAA (0.50) | MAPK14DPP4MAT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24320108 | 0.68 | ALDH1A1 (0.62) | DPP4SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL28379997 | 0.67 | SMN1; SMN2 (0.55) | MAPK14DPP4SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191834-B | Preparation method of benzo-fused N-heterocyclic compound | 中山大学 | 2020-10-16 | — | — | CN | disclosed |