Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270481 | 0.84 | ALDH1A1 (0.40) | GAAALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL290564 | 0.80 | CDC7 (0.49) | ALDH1A1KMT2AMEN1KDM4EPKM | |
| Hydrochloric Acid SCHEMBL27599188 | 0.78 | CDC7 (0.48) | ALDH1A1KMT2AMEN1KDM4EPKM | |
| SCHEMBL6128211 | 0.77 | — | — | |
| SCHEMBL4832523 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1KDM4EPKM | |
| SCHEMBL14953364 | 0.75 | KMT2A (0.44) | KMT2AACACBRAB9A | |
| SCHEMBL4095559 | 0.73 | SMN1; SMN2 (0.54) | GAAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4842407 | 0.73 | L3MBTL1 (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8690008 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1KDM4EPKM | |
| SCHEMBL81392 | 0.72 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721596-B | Phenyl-substituted dihydropyridines and their use | 广东东阳光药业有限公司 | 2020-12-18 | — | — | CN | disclosed |