Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562650 | 0.78 | FBP1 (0.35) | HCRTR1HCRTR2MBOAT4KDM4E | |
| SCHEMBL2562775 | 0.76 | MAPT (0.38) | HCRTR1HCRTR2MBOAT4ACHE | |
| SCHEMBL15607557 | 0.76 | PDE10A (0.40) | HCRTR1HCRTR2MBOAT4ACHE | |
| SCHEMBL2558428 | 0.74 | PKM (0.35) | HCRTR1HCRTR2MBOAT4KDM4EACHE | |
| SCHEMBL2564668 | 0.73 | MBOAT4 (0.37) | HCRTR1HCRTR2MBOAT4 | |
| SCHEMBL24656277 | 0.71 | PDE10A (0.36) | HCRTR1HCRTR2MBOAT4 | |
| SCHEMBL12093565 | 0.70 | KDR (0.42) | HCRTR1HCRTR2MBOAT4KDM4E | |
| SCHEMBL28804932 | 0.70 | L3MBTL1 (0.37) | HCRTR1HCRTR2MBOAT4KDM4E | |
| SCHEMBL2556721 | 0.70 | JAK2 (0.38) | HCRTR1HCRTR2MBOAT4 | |
| SCHEMBL15541410 | 0.68 | KDM4E (0.55) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112047926-A | Certain amino-pyrimidines, compositions thereof and methods of use thereof | 赛特凯恩蒂克公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-105712974-B | Certain amino-pyrimidines, compositions thereof and methods of use thereof | 赛特凯恩蒂克公司 | 2020-07-31 | — | — | CN | disclosed |