SCHEMBL28489648

SCHEMBL28489648

CCCOc1cc(C=O)ccc1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.59
CYP2C9 P11712 2/20 0.59
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
FDPS P14324 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 10/20 0.49
ADRB1 P08588 3/20 0.46
ADRB3 P13945 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
MAPT P10636 3/20 0.45
HPGD P15428 3/20 0.45
CYP1A2 P05177 1/20 0.45
HSP90AA1 P07900 1/20 0.45
CYP2C19 P33261 1/20 0.45
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
TRIM24 O15164 1/20 0.41
ALDH5A1 P51649 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28487405 0.90 NPC1 (0.58) NPSR1CYP2C9NPC1RAB9AFDPS
SCHEMBL3568653 0.88 CYP2C9 (0.59) NPSR1CYP2C9NPC1RAB9AFDPS
SCHEMBL22181800 0.87 CYP2C9 (0.55) NPSR1CYP2C9NPC1RAB9AFDPS
SCHEMBL28529318 0.81 KMT2A (0.57) NPSR1RAB9AKDM4EALDH1A1ADRB1
SCHEMBL5882634 0.80 FDPS (0.69) NPSR1CYP2C9NPC1RAB9AFDPS
SCHEMBL7992973 0.80 TSHR (0.51) CYP2C9KDM4EALDH1A1ADRB1ADRB3
SCHEMBL9527022 0.80 PTPN11 (0.56) ALDH1A1HPGDPOLB
SCHEMBL13411409 0.80 FDPS (0.63) NPSR1CYP2C9NPC1RAB9AFDPS
SCHEMBL972755 0.80 ALDH1A1 (0.76) NPSR1RAB9AFDPSKDM4EALDH1A1
SCHEMBL498271 0.79 ALDH1A1 (0.65) NPSR1CYP2C9NPC1RAB9AFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111777641-B Phosphorus-containing compound, epoxy resin composition, molding compound product, preparation method and application 中国科学院宁波材料技术与工程研究所 2020-12-11 CN disclosed
CN-111777641-A Phosphorus-containing compound, epoxy resin composition, molding compound product, preparation method and application 中国科学院宁波材料技术与工程研究所 2020-10-16 CN disclosed