Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31321666 | 0.87 | HPGD (0.56) | ALDH1A1KMT2AMEN1ATMPOLB | |
| SCHEMBL28491609 | 0.82 | ALOX15 (0.41) | ALDH1A1KMT2AMEN1ATMPOLB | |
| SCHEMBL28481675 | 0.80 | PDE4B (0.55) | ALDH1A1KMT2AMEN1ATMPOLB | |
| SCHEMBL28478306 | 0.80 | CA12 (0.53) | ALDH1A1KMT2APOLBPDE4BHPGD | |
| SCHEMBL28478128 | 0.80 | HIF1A (0.49) | ALDH1A1KMT2AMEN1ATMPOLB | |
| SCHEMBL8183705 | 0.80 | PTGS1 (0.59) | ALDH1A1KMT2ACA2LMNAHTT | |
| SCHEMBL28901969 | 0.79 | PDE4B (0.51) | ALDH1A1KMT2AMEN1POLBPDE4B | |
| SCHEMBL19900515 | 0.78 | PTGS1 (0.69) | ALDH1A1KMT2AMEN1POLBHPGD | |
| SCHEMBL31321722 | 0.78 | HPGD (0.60) | ALDH1A1KMT2APOLBHPGDLMNA | |
| SCHEMBL28487133 | 0.78 | PDE4B (0.60) | POLBPDE4BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954664-A | Cystic fibrosis transmembrane conductance regulator and methods of use | 艾伯维海外有限公司 | 2020-11-17 | — | — | CN | disclosed |