Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL925393 | 0.88 | AVPR1A (0.37) | AVPR1AABCB1CYP3A4GPR119KDM4D | |
| SCHEMBL15614743 | 0.76 | ADRB2 (0.41) | AVPR1ACYP3A4GPR119KDM4DALDH1A1 | |
| SCHEMBL13510949 | 0.76 | ADRB2 (0.41) | AVPR1ACYP3A4GPR119KDM4DALDH1A1 | |
| SCHEMBL925391 | 0.73 | MEN1 (0.32) | ABCB1GPR119 | |
| SCHEMBL14898177 | 0.73 | CA12 (0.45) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL6142523 | 0.73 | MEN1 (0.33) | ALDH1A1MAPTHPGD | |
| SCHEMBL28783308 | 0.71 | MEN1 (0.31) | GPR119 | |
| SCHEMBL960318 | 0.71 | MAPT (0.46) | ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL27530964 | 0.71 | L3MBTL1 (0.37) | ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL28255723 | 0.70 | SIGMAR1 (0.46) | SIGMAR1PTPN11CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574982-B | Method for synthesizing vilanterol intermediate under catalysis of solid acid | 安徽德信佳生物医药有限公司 | 2020-11-27 | — | — | CN | claimed |
| CN-109574982-B | Method for synthesizing vilanterol intermediate under catalysis of solid acid | 安徽德信佳生物医药有限公司 | 2020-11-27 | — | — | CN | disclosed |