Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28490290 | 0.88 | AVPR1A (0.35) | AVPR1AMAPTCYP3A4ALDH1A1GPR119 | |
| SCHEMBL6142523 | 0.84 | MEN1 (0.33) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL925100 | 0.84 | KMT2A (0.36) | MEN1KMT2AMAPTALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL6142521 | 0.80 | ALDH1A1 (0.33) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL925391 | 0.80 | MEN1 (0.32) | MEN1KMT2AGPR119ABCB1 | |
| SCHEMBL15579052 | 0.79 | MAPT (0.33) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL15614743 | 0.79 | ADRB2 (0.41) | AVPR1ACYP3A4ALDH1A1GPR119LMNA | |
| SCHEMBL28783308 | 0.79 | MEN1 (0.31) | MEN1KMT2AGPR119 | |
| SCHEMBL13510949 | 0.79 | ADRB2 (0.41) | AVPR1ACYP3A4ALDH1A1GPR119LMNA | |
| SCHEMBL27530964 | 0.78 | L3MBTL1 (0.37) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736186-A | Method for synthesizing vilanterol intermediate from tert-butyl carbamate | 安徽德信佳生物医药有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-113735816-B | Method for preparing chiral alcohol from ketone by using microchannel reactor | 安徽德信佳生物医药有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-113735816-A | Method for preparing chiral alcohol from ketone by using microchannel reactor | 安徽德信佳生物医药有限公司 | 2021-12-03 | — | — | CN | claimed |
| CN-109574982-B | Method for synthesizing vilanterol intermediate under catalysis of solid acid | 安徽德信佳生物医药有限公司 | 2020-11-27 | — | — | CN | claimed |
| US-20150239862-A1 | PROCESS FOR THE PREPARATION OF VILANTEROL AND INTERMEDIATES THEREOF | PERRIGO API LTD. (IL) | 2015-08-27 | — | — | US | claimed |
| WO-2014041565-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF VILANTEROL AND INTERMEDIATES THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2014-03-20 | — | — | WO | claimed |
| CN-114736186-B | Method for synthesizing Violet Luo Zhongjian body from tert-butyl carbamate | 安徽德信佳生物医药有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-114736186-A | Method for synthesizing vilanterol intermediate from tert-butyl carbamate | 安徽德信佳生物医药有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114736186-A | Method for synthesizing vilanterol intermediate from tert-butyl carbamate | 安徽德信佳生物医药有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-113735816-B | Method for preparing chiral alcohol from ketone by using microchannel reactor | 安徽德信佳生物医药有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-113735816-B | Method for preparing chiral alcohol from ketone by using microchannel reactor | 安徽德信佳生物医药有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-113735816-A | Method for preparing chiral alcohol from ketone by using microchannel reactor | 安徽德信佳生物医药有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-113735816-A | Method for preparing chiral alcohol from ketone by using microchannel reactor | 安徽德信佳生物医药有限公司 | 2021-12-03 | — | — | CN | disclosed |
| WO-2003072539-A1 | PHENETHANOLAMINE DERIVATIVES FOR TREATMENT OF RESPIRATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2003-09-04 | — | — | WO | disclosed |
| WO-2003035668-A2 | NOVEL ANTI-INFLAMMATORY ANDROSTANE DERIVATIVES -17-CARBOXY-LACTONE SUBSTITUTED STEROIDS WITH AN ARYL-CARBOXYLIC ESTER IN POSITION 17.ALPHA | GLAXO GROUP LIMITED (GB) | 2003-05-01 | — | — | WO | disclosed |
| WO-2003024439-A1 | PHENETHANOLAMINE DERIVATIVES FOR TREATMENT OF RESPIRATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2003-03-27 | — | — | WO | disclosed |
| WO-2002100879-A1 | NOVEL ANTI-INFLAMMATORY 17.ALPHA.-HETEROCYCLIC-ESTERS OF 17.BETA.CARBOTHIOATE ANDROSTANE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2002-12-19 | — | — | WO | disclosed |
| WO-2002088167-A1 | ANTI-INFLAMMATORY 17.BETA.-CARBOTHIOATE ESTER DERIVATIVES OF ANDROSTANE WITH A CYCLIC ESTER GROUP IN POSITION 17.ALPHA | GLAXO GROUP LIMITED (GB) | 2002-11-07 | — | — | WO | disclosed |
| WO-2002070490-A1 | AGONISTS OF BETA-ADRENOCEPTORS | GLAXO GROUP LIMITED (GB) | 2002-09-12 | — | — | WO | disclosed |
| WO-2002066422-A1 | PHENETHANOLAMINE DERIVATIVES FOR TREATMENT OF RESPIRATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239862-A1 | PROCESS FOR THE PREPARATION OF VILANTEROL AND INTERMEDIATES THEREOF | VAT1, VKORC1L1, VKORC1 | AVPR1A 16/4885MEN1 3270/4885KMT2A 3964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.