Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | TSPO | P30536 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | QPCT | Q16769 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979580 | 0.81 | CYP2C19 (0.63) | NPC1RAB9ATSPOLMNAMEN1 | |
| SCHEMBL26694572 | 0.81 | LTA4H (0.57) | ACHEMAPTLMNAMEN1KMT2A | |
| SCHEMBL24455917 | 0.80 | CYP2C19 (0.61) | TSPOACHEMAPTLMNAQPCT | |
| SCHEMBL11411386 | 0.80 | TSHR (0.58) | NPC1RAB9ALMNAALDH1A1POLB | |
| SCHEMBL11776874 | 0.80 | CYP2C19 (0.61) | TSPOACHEMAPTLMNAQPCT | |
| SCHEMBL22340523 | 0.79 | MTNR1A (0.51) | MAPTLMNAMEN1KMT2AQPCT | |
| SCHEMBL6233097 | 0.79 | APLNR (0.53) | MAPTLMNAQPCTALDH1A1APLNR | |
| SCHEMBL31288437 | 0.78 | TSPO (0.52) | NPC1RAB9ATSPOACHEMAPT | |
| SCHEMBL26694464 | 0.78 | TSPO (0.52) | NPC1RAB9ATSPOACHEMAPT | |
| SCHEMBL22340862 | 0.77 | MTNR1A (0.55) | MAPTLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049274-A2 | TETRACYCLIC DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| CN-112119075-B | Condensed ring compound | 豪夫迈·罗氏有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-112119075-A | Fused ring compound | 豪夫迈·罗氏有限公司 | 2020-12-22 | — | — | CN | disclosed |