SCHEMBL28494302

SCHEMBL28494302

CC(=O)NC(CCCCOC(N)=O)c1cc(C)c2ccccc2n1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
LMNA P02545 2/20 0.37
USP2 O75604 1/20 0.37
LTB4R Q15722 1/20 0.37
KDM4E B2RXH2 3/20 0.37
MAPT P10636 3/20 0.37
KMT2A Q03164 2/20 0.37
TACR3 P29371 2/20 0.37
GAA P10253 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
P2RY12 Q9H244 1/20 0.36
NPFFR1 Q9GZQ6 1/20 0.36
NPFFR2 Q9Y5X5 1/20 0.36
PRNP P04156 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
NPC1 O15118 1/20 0.36
TSHR P16473 1/20 0.36
GRM2 Q14416 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28494301 1.00 ALDH1A1 (0.39) ALDH1A1LMNAUSP2LTB4RKDM4E
SCHEMBL21834811 0.86 KDM4E (0.40) ALDH1A1LMNAUSP2LTB4RKDM4E
SCHEMBL21834812 0.79 MAPT (0.47) MAPTKMT2AGAANPC1
SCHEMBL21848465 0.79 MAPT (0.47) MAPTKMT2AGAANPC1
SCHEMBL21834843 0.78 FPR1 (0.47) ALDH1A1LMNAMAPTKMT2APRNP
SCHEMBL21834844 0.78 FPR1 (0.47) ALDH1A1LMNAMAPTKMT2APRNP
SCHEMBL21848423 0.77 GPR55 (0.47) ALDH1A1KDM4EMAPTKMT2ATACR3
SCHEMBL21848543 0.77 GPR55 (0.47) ALDH1A1KDM4EMAPTKMT2ATACR3
SCHEMBL21834803 0.77 GPR55 (0.47) ALDH1A1KDM4EMAPTKMT2ATACR3
SCHEMBL28487910 0.76 MAPT (0.39) ALDH1A1LMNALTB4RKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180576-B Method for photo-inducing nonmetal enantioselectively catalyzing heterocyclic aromatic hydrocarbon minisci reaction 中国科学技术大学 2020-08-25 CN disclosed