SCHEMBL28495396

SCHEMBL28495396

C[C@@H](F)CCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
POLB P06746 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
OPRK1 P41145 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CASP1 P29466 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2124923 1.00 TSHR (0.48) TSHRPOLBMEN1KMT2AALDH1A1
SCHEMBL31437678 0.83 SIGMAR1 (0.50)
SCHEMBL167715 0.80 AOC3 (0.55) TSHRPOLBMEN1KMT2AALDH1A1
SCHEMBL4785593 0.80 TSHR (0.52) TSHRPOLBMEN1KMT2AALDH1A1
SCHEMBL4192452 0.80 HTR2A (0.52) ALDH1A1HPGDCYP1A2CYP2C19SMN1; SMN2
SCHEMBL10697566 0.80 TSHR (0.52) TSHRPOLBMEN1KMT2AALDH1A1
Ammonia Solution, Strong SCHEMBL4461727 0.78 AOC3 (0.53) TSHRPOLBMEN1KMT2AALDH1A1
Hydrogen Peroxide SCHEMBL9581085 0.78 TSHR (0.55) TSHRPOLBMEN1KMT2AHPGD
SCHEMBL12020759 0.77 KCNH2 (0.49) POLBMEN1KMT2A
SCHEMBL23531244 0.76 TSHR (0.48) TSHRPOLBMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903112-A Sulfur-containing deoxidized fluoridation reagent and preparation method and application thereof 铜陵学院 2024-04-19 CN disclosed
CN-112062670-B Fluorination reagent and deoxidization fluorination method 三明市海斯福化工有限责任公司 2023-05-09 CN disclosed
CN-112062670-A Fluorination reagent and deoxidation fluorination method 三明市海斯福化工有限责任公司 2020-12-11 CN disclosed