Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 18/20 | 0.62 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.47 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15412791 | 0.83 | FGFR4 (0.69) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL29385382 | 0.83 | FGFR4 (0.69) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL16683513 | 0.80 | FGFR4 (0.67) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL16676911 | 0.78 | FGFR4 (0.66) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL21153635 | 0.77 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL16674626 | 0.76 | FGFR4 (0.63) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL21154002 | 0.76 | FGFR4 (0.60) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL21154059 | 0.74 | FGFR4 (0.56) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL21153921 | 0.74 | FGFR4 (0.60) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL21153337 | 0.72 | FGFR4 (0.57) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028491-B | Fibroblast growth factor receptor inhibitors | 缆图药品公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-107793395-B | Fibroblast growth factor receptor inhibitors and uses thereof | 南京药捷安康生物科技有限公司 | 2021-01-05 | — | — | CN | disclosed |