SCHEMBL28495674

SCHEMBL28495674

CCOS(=O)(=O)c1ccccc1[SiH3]

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
GLA P06280 1/20 0.34
GAA P10253 2/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PSIP1 O75475 1/20 0.33
PTPN1 P18031 3/20 0.33
PTPRC P08575 1/20 0.33
CDC25B P30305 1/20 0.33
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CA12 O43570 2/20 0.32
CA7 P43166 2/20 0.32
CA9 Q16790 2/20 0.32
CYP2C9 P11712 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL778991 0.86 GAA (0.39) ALDH1A1L3MBTL1GAAMAPK1TDP1
SCHEMBL29415266 0.86 GAA (0.39) ALDH1A1L3MBTL1GAAMAPK1TDP1
SCHEMBL28494154 0.85 CA1 (0.36) ALDH1A1L3MBTL1PSIP1CA1CA2
SCHEMBL2906066 0.78 CTSB (0.47) L3MBTL1GAAPSIP1CA1CA2
SCHEMBL8712194 0.78 HSD11B1 (0.43) ALDH1A1L3MBTL1GAACYP2C9HSD17B10
SCHEMBL582357 0.78 KMT2A (0.44) ALDH1A1L3MBTL1GAACYP2C9MEN1
SCHEMBL8779870 0.78 GAA (0.54) ALDH1A1GAACA1CA2CA12
SCHEMBL28612611 0.78 HTR6 (0.37) ALDH1A1GAATDP1CDC25BCA1
SCHEMBL28384350 0.77 CA1 (0.40) ALDH1A1GAATDP1CA1CA2
SCHEMBL10846783 0.77 TRPV4 (0.37) ALDH1A1L3MBTL1GAAMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112143028-B Application of substituted silicon-based benzene sulfonate in flame-retardant modification of high polymer material and flame-retardant high polymer material 中国科学院宁波材料技术与工程研究所 2021-07-27 CN disclosed
CN-112143028-A Application of substituted silicon-based benzene sulfonate in flame-retardant modification of high polymer material and flame-retardant high polymer material 中国科学院宁波材料技术与工程研究所 2020-12-29 CN disclosed