SCHEMBL2849636

SCHEMBL2849636

CCOC(=O)CC(C(=O)OCC)C(C)(C)C1CCCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.46
KMT2A Q03164 1/20 0.37
UGT2B7 P16662 2/20 0.36
FKBP1A P62942 2/20 0.35
ALDH1A1 P00352 7/20 0.35
TSHR P16473 3/20 0.35
CYP3A4 P08684 2/20 0.35
ALOX15 P16050 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
CHRM1 P11229 1/20 0.34
ADORA1 P30542 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
METAP2 P50579 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2859945 0.82 RAB9A (0.35) CYP2D6TSHR
SCHEMBL25198909 0.77 CYP2D6 (0.40) CYP2D6FKBP1AALDH1A1TSHRNPSR1
SCHEMBL1244569 0.76 GAA (0.44) CYP2D6KMT2AALDH1A1TSHRCYP3A4
SCHEMBL27495623 0.76 MAPT (0.34) FKBP1ACHRM1NPSR1L3MBTL1
SCHEMBL6483909 0.73 KMT2A (0.41) CYP2D6KMT2AFKBP1AALDH1A1TDP1
SCHEMBL12691593 0.73 MMP8 (0.37) CYP2D6FKBP1AALDH1A1TSHRNPSR1
SCHEMBL25517969 0.73 ALDH1A1 (0.37) CYP2D6FKBP1AALDH1A1TSHRCHRM1
SCHEMBL25536207 0.73 TSHR (0.38) CYP2D6FKBP1AALDH1A1TSHRCHRM1
SCHEMBL28248202 0.73 ALDH1A1 (0.44) CYP2D6KMT2AALDH1A1TSHRCYP3A4
SCHEMBL974546 0.71 GAA (0.40) CYP2D6ALDH1A1TSHRCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822366-B2 Solid titanium catalyst component, catalyst for olefin polymerization and process for polymerizing olefin MITSUI CHEMICALS, INC. (JP) 2014-09-02 US disclosed
EP-2206731-B1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD MITSUI CHEMICALS INC (JP) 2013-08-28 EP disclosed
CN-101842396-B Solid titanium catalyst component, olefin polymerization catalyst, and olefin polymerization method MITSUI CHEMICALS INC 2013-03-20 CN disclosed
CN-101842396-A Solid titanium catalyst component, olefin polymerization catalyst, and olefin polymerization method MITSUI CHEMICALS INC 2010-09-22 CN disclosed
US-20100227991-A1 SOLID TITANIUM CATALYST COMPONENT, CATALIST FOR OLEFIN POLYMERIZATION AND PROCESS FOR POLYMERIZING OLEFIN MITSUI CHEMICALS, INC. (JP) 2010-09-09 US disclosed
EP-2206731-A1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD Mitsui Chemicals, Inc. (JP) 2010-07-14 EP disclosed
CN-1285623-C Catalyst system for olefin polymerization BASELL POLIOLEFINE SPA (IT) 2006-11-22 CN disclosed
CN-1545525-A Catalyst system for olefin polymerization ��������ϩ����������޹�˾ 2004-11-10 CN disclosed