SCHEMBL25536207

SCHEMBL25536207

CCOC(=O)C(C(=O)O)C(C)(C)C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ALDH1A1 P00352 4/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 3/20 0.36
FKBP1A P62942 2/20 0.36
METAP2 P50579 1/20 0.36
THRB P10828 1/20 0.36
ATM Q13315 1/20 0.36
SLC6A2 P23975 3/20 0.35
SLC6A3 Q01959 3/20 0.35
SLC6A4 P31645 2/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25198909 0.92 CYP2D6 (0.40) TSHRALDH1A1NPSR1L3MBTL1FKBP1A
SCHEMBL25517969 0.87 ALDH1A1 (0.37) TSHRALDH1A1NPSR1L3MBTL1FKBP1A
SCHEMBL2152295 0.83 L3MBTL1 (0.39) ALDH1A1NPSR1L3MBTL1FKBP1ACYP2D6
SCHEMBL25517970 0.78 EPHX1 (0.33)
SCHEMBL12691593 0.75 MMP8 (0.37) TSHRALDH1A1NPSR1L3MBTL1FKBP1A
SCHEMBL16732122 0.74 ALDH1A1 (0.41) ALDH1A1L3MBTL1FKBP1ATHRBATM
SCHEMBL2849636 0.73 CYP2D6 (0.46) TSHRALDH1A1NPSR1L3MBTL1FKBP1A
SCHEMBL3375066 0.73 MAPT (0.35)
SCHEMBL3212385 0.73 ALDH1A1 (0.40) ALDH1A1L3MBTL1SLC6A3CHRM1CHRM3
SCHEMBL24677537 0.72 CYP2D6 (0.38) TSHRALDH1A1NPSR1L3MBTL1FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159453-A1 INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION COCRYSTAL PHARMA, INC. 2023-05-25 US disclosed
US-20230159453-A1 INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION COCRYSTAL PHARMA, INC. 2023-05-25 US disclosed
EP-4132944-A1 INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION Cocrystal Pharma, Inc. (US) 2023-02-15 EP disclosed
CN-115698035-A Inhibitors of norovirus and coronavirus replication 共晶制药公司 2023-02-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159453-A1 INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION VIM, ACE, ACE2 TSHR 4620/4885ALDH1A1 1895/4885NPSR1 3186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.