SCHEMBL28498010

SCHEMBL28498010

O=c1[nH]c(=O)n(C(OCC(O)CO)C(O)(OCC(O)CO)OCC(O)CO)c(=O)[nH]1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 1/20 0.30
PDE3A Q14432 1/20 0.30
P2RY12 Q9H244 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28064026 0.68 PDE3B (0.35) PDE3BPDE3AP2RY12
SCHEMBL9743284 0.65 TYMP (0.31)
SCHEMBL13413739 0.62 MMP9 (0.36)
Glycerin SCHEMBL28078451 0.61 LMNA (0.53) PDE3BPDE3AP2RY12
SCHEMBL5605627 0.61
SCHEMBL11757540 0.60 LMNA (0.30)
SCHEMBL27561102 0.60 LMNA (0.42)
SCHEMBL11690765 0.60 POLB (0.33)
SCHEMBL11695516 0.60 THRB (0.34)
SCHEMBL27966008 0.59 KDM4E (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107922605-B Polyrotaxane, process for producing the same, and optical composition containing the same 株式会社德山 2020-12-11 CN disclosed