Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10671847 | 0.81 | ALDH1A1 (0.35) | ALDH1A1SOAT1 | |
| SCHEMBL28498359 | 0.80 | CHRM2 (0.40) | — | |
| SCHEMBL27413130 | 0.80 | CHRM2 (0.40) | — | |
| SCHEMBL2330898 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SOAT1LMNASLC6A2SLC6A4 | |
| SCHEMBL4014963 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SOAT1LMNASLC6A2SLC6A4 | |
| SCHEMBL9054793 | 0.78 | SLC6A2 (0.43) | ALDH1A1SOAT1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2567582 | 0.78 | SLC6A2 (0.43) | ALDH1A1SOAT1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7297987 | 0.78 | L3MBTL1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL16774678 | 0.76 | L3MBTL1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL28222584 | 0.74 | SOAT1 (0.40) | ALDH1A1SOAT1TRPM8KDM4ESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555824-A1 | N-alpha-arylsulfonylated benzimidazolylalaninamide derivatives, medicaments based thereon and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |