SCHEMBL28498447

SCHEMBL28498447

NN(Cl)c1c[nH]c2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MITF O75030 1/20 0.47
ATM Q13315 2/20 0.47
LMNA P02545 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
CYP3A4 P08684 3/20 0.45
MAPT P10636 2/20 0.45
GPR84 Q9NQS5 2/20 0.45
AHR P35869 1/20 0.45
HTT P42858 1/20 0.44
HTR2A P28223 5/20 0.44
HTR2C P28335 5/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2A6 P11509 2/20 0.44
HTR1D P28221 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4953238 0.79 ALDH1A1 (0.51) ALDH1A1MEN1KMT2ATDP1NPC1
SCHEMBL7973209 0.77 CYP2A6 (0.50) ALDH1A1MEN1KMT2ATDP1NPC1
SCHEMBL28229484 0.77 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ATDP1NPC1
SCHEMBL4212837 0.77 ATM (0.54) ALDH1A1MEN1KMT2ATDP1NPC1
SCHEMBL21921279 0.77 ATM (0.48) ALDH1A1MEN1KMT2ATDP1NPC1
SCHEMBL30171037 0.77 ATM (0.54) ALDH1A1MEN1KMT2ATDP1NPC1
SCHEMBL7970007 0.74 LMNA (0.57) ALDH1A1MEN1KMT2ATDP1NPC1
SCHEMBL10617441 0.73 MEN1 (0.58) ALDH1A1MEN1KMT2ATDP1NPC1
SCHEMBL15602070 0.73 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ATDP1NPC1
SCHEMBL6321754 0.73 ALDH1A1 (0.54) ALDH1A1MEN1KMT2ATDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112021326-A Bactericidal composition containing chlorine indole hydrazide and agricultural streptomycin and application thereof 京博农化科技有限公司 2020-12-04 CN disclosed