Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617441 | 0.81 | MEN1 (0.58) | ALDH1A1MEN1KMT2ATDP1NPC1 | |
| SCHEMBL28498447 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ATDP1NPC1 | |
| SCHEMBL7973209 | 0.73 | CYP2A6 (0.50) | ALDH1A1MEN1KMT2ATDP1NPC1 | |
| SCHEMBL28229484 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ATDP1NPC1 | |
| SCHEMBL30171037 | 0.72 | ATM (0.54) | ALDH1A1MEN1KMT2ATDP1NPC1 | |
| SCHEMBL4212837 | 0.72 | ATM (0.54) | ALDH1A1MEN1KMT2ATDP1NPC1 | |
| SCHEMBL21921279 | 0.72 | ATM (0.48) | ALDH1A1MEN1KMT2ATDP1NPC1 | |
| SCHEMBL3423737 | 0.70 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATDP1NPC1 | |
| SCHEMBL11387418 | 0.70 | KIF11 (0.47) | ALDH1A1MEN1KMT2ATDP1NPC1 | |
| SCHEMBL7970007 | 0.70 | LMNA (0.57) | ALDH1A1MEN1KMT2ATDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045952-A2 | PHOTORECEPTOR PRECURSOR CELLS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2008-04-17 | — | — | WO | disclosed |
| EP-1226116-A1 | PROCESSES FOR THE PREPARATION OF SUMATRIPTAN AND RELATED COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001034561-A1 | PROCESSES FOR THE PREPARATION OF SUMATRIPTAN AND RELATED COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-17 | — | — | WO | disclosed |