Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27407793 | 0.79 | IMPDH2 (0.50) | CYP2A6IMPDH2ALDH1A1MEN1KMT2A | |
| SCHEMBL28498447 | 0.77 | ALDH1A1 (0.47) | CYP2A6IMPDH2ALDH1A1MEN1KMT2A | |
| SCHEMBL28229484 | 0.75 | ALDH1A1 (0.43) | CYP2A6IMPDH2ALDH1A1MEN1KMT2A | |
| SCHEMBL4953238 | 0.73 | ALDH1A1 (0.51) | CYP2A6ALDH1A1MEN1KMT2AATM | |
| SCHEMBL7970007 | 0.72 | LMNA (0.57) | ALDH1A1MEN1KMT2AATMNPC1 | |
| SCHEMBL28605397 | 0.71 | CYP2A6 (0.42) | CYP2A6IMPDH2ALDH1A1MEN1KMT2A | |
| SCHEMBL5260586 | 0.71 | NPC1 (0.47) | CYP2A6IMPDH2ALDH1A1MEN1KMT2A | |
| SCHEMBL4212837 | 0.71 | ATM (0.54) | CYP2A6IMPDH2ALDH1A1MEN1KMT2A | |
| SCHEMBL21921279 | 0.71 | ATM (0.48) | CYP2A6IMPDH2ALDH1A1MEN1KMT2A | |
| SCHEMBL30171037 | 0.71 | ATM (0.54) | CYP2A6IMPDH2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603188-A | Indole and quinoline skeleton-containing compound and application thereof | 苏州卫生职业技术学院 | 2024-02-27 | — | — | CN | claimed |
| CN-114591295-B | Pyridine salt-containing N- (indolyl) -N' - (substituted) propyl hydrazide derivative, preparation method and application thereof | 贵州大学 | 2023-11-07 | — | — | CN | claimed |
| CN-114591295-A | Pyridine salt-containing N- (indoleacyl) -N' - (substituted) propyl hydrazide derivative, and preparation method and application thereof | 贵州大学 | 2022-06-07 | — | — | CN | claimed |
| CN-107235966-B | A kind of bis- indoles -1,2,4- triazole ketone compounds of 3,4- and its preparation method and application | 浙江工业大学 | 2019-12-03 | — | — | CN | claimed |
| CN-107593732-A | A kind of preventing and treating plant virus composition containing Ningnanmycin | 京博农化科技股份有限公司 | 2018-01-19 | — | — | CN | claimed |
| CN-107568233-A | A kind of bactericidal composition containing amino-oligosaccharide | 京博农化科技股份有限公司 | 2018-01-12 | — | — | CN | claimed |
| CN-107235966-A | Triazole ketone compounds of one indoles of class 3,4 pairs 1,2,4 and its preparation method and application | 浙江工业大学 | 2017-10-10 | — | — | CN | claimed |
| CN-104744460-B | β carbolines, dihydro β carbolines and tetrahydro-beta-carboline alcaloid-derivatives and preparation method thereof and the application in terms of preventing and treating plant virus, sterilization, desinsection | 南开大学 | 2017-06-16 | — | — | CN | claimed |
| CN-117603188-A | Indole and quinoline skeleton-containing compound and application thereof | 苏州卫生职业技术学院 | 2024-02-27 | — | — | CN | disclosed |
| CN-114478537-A | Cyclic amide-fused ring compound and medical use thereof | 上海拓界生物医药科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-110759913-B | Indolylhydrazone derivatives, preparation method thereof and application thereof in plant virus prevention and control, sterilization and disinsection | 南开大学 | 2022-01-28 | — | — | CN | disclosed |
| CN-110759913-A | Indolylhydrazone derivatives, preparation method thereof and application thereof in plant virus prevention and control, sterilization and disinsection | 南开大学 | 2020-02-07 | — | — | CN | disclosed |
| CN-107235966-B | A kind of bis- indoles -1,2,4- triazole ketone compounds of 3,4- and its preparation method and application | 浙江工业大学 | 2019-12-03 | — | — | CN | disclosed |
| CN-107235966-B | A kind of bis- indoles -1,2,4- triazole ketone compounds of 3,4- and its preparation method and application | 浙江工业大学 | 2019-12-03 | — | — | CN | disclosed |
| CN-107235966-A | Triazole ketone compounds of one indoles of class 3,4 pairs 1,2,4 and its preparation method and application | 浙江工业大学 | 2017-10-10 | — | — | CN | disclosed |
| CN-107235966-A | Triazole ketone compounds of one indoles of class 3,4 pairs 1,2,4 and its preparation method and application | 浙江工业大学 | 2017-10-10 | — | — | CN | disclosed |
| CN-104744460-B | β carbolines, dihydro β carbolines and tetrahydro-beta-carboline alcaloid-derivatives and preparation method thereof and the application in terms of preventing and treating plant virus, sterilization, desinsection | 南开大学 | 2017-06-16 | — | — | CN | disclosed |
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |