Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28493442 | 0.82 | KMT2A (0.49) | MAPTGAAHPGDKMT2AMEN1 | |
| SCHEMBL28489905 | 0.80 | PKM (0.49) | GAAHPGDKMT2AMEN1 | |
| SCHEMBL28497453 | 0.77 | CYP3A4 (0.43) | MAPTGAACYP3A4KMT2AMEN1 | |
| SCHEMBL28487989 | 0.77 | MAPT (0.54) | MAPTGAAHPGDKMT2AMEN1 | |
| SCHEMBL28497517 | 0.77 | MAPT (0.49) | MAPTGAAHPGDKMT2AMEN1 | |
| SCHEMBL28498697 | 0.77 | KMT2A (0.44) | GAAHPGDKMT2AMEN1 | |
| SCHEMBL28491345 | 0.76 | SMN1; SMN2 (0.58) | MAPTGAAHPGDCYP1A2CYP3A4 | |
| SCHEMBL28904711 | 0.72 | KMT2A (0.48) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28491357 | 0.72 | KMT2A (0.42) | MAPTGAAHPGDKMT2AMEN1 | |
| SCHEMBL6970033 | 0.72 | L3MBTL1 (0.64) | MAPTGAAKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110932-B | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2021-12-28 | — | — | CN | disclosed |
| CN-112110932-A | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2020-12-22 | — | — | CN | disclosed |